Document 1820 DOCN M94A1820 TI Impact of socio-economic factors as adjuvant in AIDS-treatment. A follow up of 18 patients taking Retrovir. DT 9412 AU Minlangu M; Nzila M; Kapita B; Projet Sida/Kinshasa-Zaire, Antwerpen, Belgium. SO Int Conf AIDS. 1994 Aug 7-12;10(1):444 (abstract no. PD0383). Unique Identifier : AIDSLINE ICA10/94370755 AB OBJECTIVES: To determine the role of the surroundings of african AIDS-patients. To demonstrate how economic problems could depress patients, and adopting a negative behavior. METHODS: Between 1988-1989, African AIDS-patients were recruited for Retrovir trial. All cases were selected and had to give a written consent associating a third person who was utilized as psychological adjuvant. The cohort is being followed up, until the last patient will died, by a physician and four nurses. They have been hospitalized for the first three weeks then assessed once a month or anytime problems occurred. RESULTS: 7 men and 11 women, 24-46 years old, who had experienced already at least one of these opportunistic infections: candidiasis, herpes-zoster, TBC, pneumocytisis ..., etc ... were enrolled to a Retrovir trial. Evolution: 2/18 (11.1%) excluded, 2/16 (12.5%) was lost for follow up by refusing collaboration when the surroundings knew that they were HIV(+), 4/16 died before one year of follow up, 5/16 (31.8%) died in the second year, 5/16 (31.8%) overtopped 2 years amongst them 3 (18.8%) are still a live. 6/18 (33.3%) hastened their death by refusing collaboration after committing a breach of their confidences. 5/18 (27.8%) fell down consequently to the national economic depression. CONCLUSION: Whatever retrovir seem to ameliorate the general status, the surroundings are a lot of to do for improving of AIDS-patient health care. DE Acquired Immunodeficiency Syndrome/*DRUG THERAPY/PSYCHOLOGY Adult Cohort Studies Female Follow-Up Studies Human Male Middle Age Social Support Socioeconomic Factors Zaire Zidovudine/*THERAPEUTIC USE CLINICAL TRIAL MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).